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Amphetamine is understood to inhibit monoamine oxidase, whereas the power of amphetamine and its metabolites to inhibit numerous P450 isozymes and other enzymes hasn't been sufficiently elucidated. In vitro experiments with human microsomes show minor inhibition of CYP2D6 by amphetamine and minimal inhibition of CYP1A2, 2D6, and 3A4 by one or more